COVID-19 Vaccination: What Do We Know So far?


  • The Covid-19 vaccines from Moderna and Biontech / Pfizer are the first approved vaccines based on mRNA. 
  • Possible long-term consequences or long-term side effects are still frequent arguments from many non-vaccinated persons. Data from 6.2 million vaccinated persons examined shows, no direct, or serious side effects. This has been shown by the ongoing security monitoring in the USA.
  • Most vaccine effects occur immediately or within hours after vaccination – for example, fever or allergies.
  • Long-term consequences cause long-term or permanent damage. They usually appear a few weeks after the vaccination.
  • There are no indications of long-term consequences after one and a half years of study data. The monitoring continues.

To date, more than 6.5 billion vaccine doses have been administered worldwide to protect against Covid-19. A large part is based on the so-called mRNA vaccines that are being used for the first time against the Sars-CoV-2 coronavirus. The mRNA technology has been researched for a long time, but it was only the urgency of the pandemic and the money brought in that ensured that the development could be accelerated to such an extent that it was approved after a few months.


It is now well known that vaccination reactions can occur after vaccination, which can be unpleasant but usually disappear again quickly. Also that after receiving one of the two mRNA vaccines, in rare cases side effects such as inflammation of the heart muscle (myocarditis) or pericardial sac (pericarditis) can occur, which – recognized in good time – can be treated well.

Researchers from various private and government US institutions have now evaluated using data from 6.2 million people who had received either the vaccine from Moderna or Biontech / Pfizer. In doing so, they focused on serious health problems that have occurred before in connection with a Covid-19 vaccination. These include heart attacks, strokes, blood clots, facial paralysis ( Bell’s Palsy ), severe allergic reactions ( anaphylaxis ) and Guillain-Barré syndrome.


Result: Compared to unvaccinated people and people who had been vaccinated with an mRNA vaccine more than three weeks previously, those who had received their vaccination in the past few weeks showed no more serious health effects. In some cases, the people whose data was included in the investigation did experience serious problems. However, there was no evidence that these were caused by the vaccine. “The signal threshold above which a side effect occurs statistically significant was not exceeded,” said the researchers.

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